American Journal of Heterocyclic Chemistry

Volume 4, Issue 2, June 2018

  • Fatty Acids in Heterocyclic Synthesis: Part XIX Synthesis of Some Isoxazole, Pyrazole, Pyrimidine and Pyridine and Their Surface, Anticancer and Antioxidant Activities

    Abdelmotaal Abdelmajeid, Mahasen Saad Amine, Reda Ali Hassan

    Issue: Volume 4, Issue 2, June 2018
    Pages: 30-41
    Received: Mar. 12, 2018
    Accepted: Apr. 11, 2018
    Published: Jul. 03, 2018
    Abstract: Acryloylphenylstearamide (2) was utilized as a starting material for synthesis the titled compounds via one-pot synthesis. Compound (2) was reacted with hydroxylamine hydrochloride in pyridine and produced isooxazole (3), and with thiosemicarbazide in pyridine and/or hydrazine-hydrate in ethanol afforded pyrazoles (4), and (5), while the reaction o... Show More