American Journal of Heterocyclic Chemistry

Volume 5, Issue 4, December 2019

  • Synthesis of Barbituric and Thiobarbituric Acids Bearing 5,6-Diphenyl-1,2,4-Triazin-3-yl Moiety as CDK2 Inhibitors of Tumor Cells

    Dina Abed Bakhotmah

    Issue: Volume 5, Issue 4, December 2019
    Pages: 76-80
    Received: Aug. 27, 2019
    Accepted: Sep. 10, 2019
    Published: Oct. 11, 2019
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    Abstract: Synthesis of several new diphenyl-1',2',4'-triazin-3'-yl barbituric acid are described. The method involves addition reaction of isocyanate and isothiocyanate and 3-amino-5,6-diphenyl-1,2,4-triazine (1) to give N1,N3-disubstituted urea 2 and N1,N3-disubstituted thioureas 3 and 4 respectively. Further, ring closure reactions with malonate ester give... Show More
  • Synthesis, Infrared and Mössbauer Characterization of Some Chloridestannate (IV) Inorganic-organic Hybrid Complexes: Sn-Ph Bonds Cleavage

    Dame Seye, Mouhamadou Birame Diop, Assane Toure, Tidiane Diop, Cheikh Abdoul Khadir Diop, Mamadou Sidibe, Aminata Diasse Sarr, Libasse Diop

    Issue: Volume 5, Issue 4, December 2019
    Pages: 81-85
    Received: Feb. 13, 2020
    Accepted: Feb. 27, 2020
    Published: Mar. 10, 2020
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    Abstract: Five new compounds are isolated from reactions carried out in solution. All the compounds are characterized by, Infrared and Mössbauer spectroscopies. Spectroscopic studies have shown the presence of different carracterristic bands, notably υ (PO) vibrations coming from triphenylphosphine oxide, with wide absorption due to the NH2 groups coming fro... Show More