American Journal of Heterocyclic Chemistry

Volume 7, Issue 2, December 2021

  • Syntheses, Complexation and Biological Activity of Aminopyridines: A Mini-Review

    Kingsley John Orie, Remy Ukachukwu Duru, Raphael I-oro Ngochindo

    Issue: Volume 7, Issue 2, December 2021
    Pages: 11-25
    Received: Jun. 19, 2021
    Accepted: Jul. 01, 2021
    Published: Jul. 09, 2021
    Abstract: Aminopyridines are among the classes of heterocyclic compounds that have been extensively studied in the last few decades owing to their interesting biological activities. They exist in three isomeric forms: 2-aminopyridine, 3-aminopyridine and 4-aminopyridine. The diversity in their pharmacological activities has attracted the attention of many re... Show More
  • 3-Oxobutanamides in Heterocyclic Synthesis: Synthesis, Antimicrobial and Antioxidant Activity of Pyridine, Thiophene, Diazepine and Thiazole Derivatives

    Sayed Abd El-moneim Ahmed Altaweel, Ahmed Abdelhameed Khames, Abu-Bakr Abdelhady Mohamed El-Adasy, Abdallah Mahmoud Ahmed Hassane, Abdel-Haleem Mostafa Hussein

    Issue: Volume 7, Issue 2, December 2021
    Pages: 26-32
    Received: Mar. 18, 2021
    Accepted: Jul. 09, 2021
    Published: Jul. 15, 2021
    Abstract: In the last few years we and others reported a variety of synthesis of heteroaromatics that have been developed utilizing β–oxoanilides as readily obtainable compounds. In this study, treatment of 3-Oxobutanamides 1 with phenyl isocyanate at room temperature in basic medium and DMF afforded thiocarbamoyl derivative 3 through intermediate 2 upon tre... Show More
  • Some Aspects of the Reactivity of 3-acyl-4-hydroxycoumarins

    Youssoufou Bakouan, Bintou Sessouma, Têeda Hamidou Ganamé, Lassané Tarpaga, Jules Yoda, Karifa Bayo

    Issue: Volume 7, Issue 2, December 2021
    Pages: 33-38
    Received: Nov. 08, 2021
    Accepted: Dec. 02, 2021
    Published: Dec. 07, 2021
    Abstract: Coumarins are the most important oxygenated heterocyclic of natural compounds. They are widely used as raw materials in many areas such as agrochemical, perfume, pharmaceutical industries. They therefore have several physical, chemical and biological properties. In order to enlarge this family of compounds and elucidate almost all of its properties... Show More