American Journal of Heterocyclic Chemistry

Volume 5, Issue 3, September 2019

  • Organotellurium Chemistry: Synthesis and Properties of 2-Acylamino- and 2-Arylamino-1,3-benzotellurazoles

    Whitney Elisabeth Smith, Donna Victoria Franklin, Kourtni Lynn Goutierrez, Frank Robert Fronczek, Franz Andreas Mautner, Thomas Junk

    Issue: Volume 5, Issue 3, September 2019
    Pages: 49-54
    Received: Dec. 06, 2018
    Accepted: Jul. 10, 2019
    Published: Jul. 30, 2019
    Abstract: Synthetic methods have been developed to prepare novel 1,3-benzotellurazoles carrying acylamino and arylamino moieties in position 2, in order to investigate their propensity to self-assemble to supramolecular structures. The targeted compounds were obtained in yields ranging from 44% to 67%, by reacting bis(2-aminophenyl) ditelluride with acyl- an... Show More
  • In vitro Anti Leukemia Cancer Activity of Some Novel Pyrazole Derivatives and Pyrazoles Containing Thiazole Moiety

    Amal Mahmoud Youssef Moustafa

    Issue: Volume 5, Issue 3, September 2019
    Pages: 55-70
    Received: Jun. 30, 2019
    Accepted: Aug. 01, 2019
    Published: Aug. 14, 2019
    Abstract: The design and syntheses of several novel pyrazole derivatives (2, 5, 6 and 7) and pyrazole derivatives (3 and 4) containing thiazole moiety via by ethyl β-(p-chlorophenyl)–α-cyanoacrylate (1) and thiosemicarbazide as starting materials. Pyrazole derivatives (3 and 4) containing thiazole moiety were synthesized via cyclization of pyrazole derivativ... Show More
  • Green Synthesis and Antibacterial Activity of Pyrido[2,3-e]1,3,4-Oxadiazine Derivatives

    Fayez Mohamed Eissa, Mohamed Selim, Ahmed Sayed, Mohamed Sharkawi

    Issue: Volume 5, Issue 3, September 2019
    Pages: 71-75
    Received: Jun. 22, 2019
    Accepted: Jul. 13, 2019
    Published: Aug. 23, 2019
    Abstract: Pyrido[2,3-e]1,3,4-Oxadiazines heterocyclic ring system and its derivatives were efficiently synthesized via benign and sustainable methodology using Grinding Chemistry as a recognized solvent free, less hazard, and low risk pathway. The course of the reaction was completed by refluxing using ecofriendly and renewable source of initiation energy vi... Show More